Proteomic Applications in Cancer Detection and Discovery

Preface vii

Acknowledgments ix

1 Systems Biology 1

2 Mass Spectrometry in Cancer Research 27

3 Quantitative Proteomics 59

4 Proteomic Analysis of Posttranslational Modifications 87

5 Characterization of Protein Complexes 117

6 Global Phosphorylation Analysis 145

7 the Search for Biomarkers in Biofluids 171

8 Proteomic Patterns: a New Paradigm in Diagnostics And Therapeutics? 195

9 the Emergence of Protein Arrays 215

10 the Role of Proteomics in Personalized Medicine 241

11 the Critical Role of Bioinformatics 263

12 Future Prospects of Proteomics in Cancer Research 281

Index 305

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• Pesquisa médica
• Proteinas
• Oncologia

researchers; work; proteomics; cancer; increasingly important; progression; cure; proteomic; origin; data; oncologic researchers; themselves; studies; result; scientists; between; knowledge gap; interpret