Drug-DNA Interactions
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portes grátis
Drug-DNA Interactions
Structures and Spectra
Strahan, Gary D.; Tsuboi, Masamichi; Nakamoto, Kazuo
John Wiley & Sons Inc
09/2008
400
Dura
Inglês
9780471786269
15 a 20 dias
690
Descrição não disponível.
Preface. Introduction.
1. DNA Structures and Spectra.
1.1. DNA Structures.
1.2. Electronic Spectra.
1.3. Vibrational Spectra.
1.4. NMR Spectra.
1.5. Electron Spin Resonance Spectra.
1.6. X-Ray Crystallography.
1.7. Molecular Modeling an molecular Mechanics.
2. Intercalating Drugs.
2.1. Acridine Dyes.
2.2. Ethidium Bromide.
2.3. Aclacinomycin.
2.4. Sequence Preference.
2.5. Bis- and Tris- Intercalators.
3. Groove- Binding Drugs.
3.1. Netropsin and Distamycin.
3.2. Derivatives of Netropsin and Distamycin.
3.3. Hoechst 33258, SN6999, and their Derivatives.
3.4. Chromomycin, Mithramycin, and Other GC Binders.
3.5. Groove Binding and Intercalation.
4. Covalent Bonding Drugs.
4.1. (+) CC1065 and Related Drugs.
4.2. Anthramycin and Tomaymycin.
4.3. Ecteinascidins.
4.4. Mitomycins.
4.5. Intercalating Alkylators.
5. Strand-Breaking Drugs.
5.1. Bleomycins.
5.2. Enediyne Antibiotics.
6. Metal-Containing Drugs.
6.1. Cisplatin.
6.2. Cisplatin Derivatives.
6.3. Transplatin and Derivatives.
6.4. Monofunctional Platinum Complexes.
6.5. Polynuclear and High-valent Platinum Complexes.
6.6. Complexes Containing Other Metals.
Appendixes.
Index.
1. DNA Structures and Spectra.
1.1. DNA Structures.
1.2. Electronic Spectra.
1.3. Vibrational Spectra.
1.4. NMR Spectra.
1.5. Electron Spin Resonance Spectra.
1.6. X-Ray Crystallography.
1.7. Molecular Modeling an molecular Mechanics.
2. Intercalating Drugs.
2.1. Acridine Dyes.
2.2. Ethidium Bromide.
2.3. Aclacinomycin.
2.4. Sequence Preference.
2.5. Bis- and Tris- Intercalators.
3. Groove- Binding Drugs.
3.1. Netropsin and Distamycin.
3.2. Derivatives of Netropsin and Distamycin.
3.3. Hoechst 33258, SN6999, and their Derivatives.
3.4. Chromomycin, Mithramycin, and Other GC Binders.
3.5. Groove Binding and Intercalation.
4. Covalent Bonding Drugs.
4.1. (+) CC1065 and Related Drugs.
4.2. Anthramycin and Tomaymycin.
4.3. Ecteinascidins.
4.4. Mitomycins.
4.5. Intercalating Alkylators.
5. Strand-Breaking Drugs.
5.1. Bleomycins.
5.2. Enediyne Antibiotics.
6. Metal-Containing Drugs.
6.1. Cisplatin.
6.2. Cisplatin Derivatives.
6.3. Transplatin and Derivatives.
6.4. Monofunctional Platinum Complexes.
6.5. Polynuclear and High-valent Platinum Complexes.
6.6. Complexes Containing Other Metals.
Appendixes.
Index.
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drugdna; information; guide; informative; basis; empirical; structural; source; thorough; interactions; underlying mechanisms; readers; lesser; design; drugs; efficient; research; new; expediting; side effects; gleaned; logical; wealth
Preface. Introduction.
1. DNA Structures and Spectra.
1.1. DNA Structures.
1.2. Electronic Spectra.
1.3. Vibrational Spectra.
1.4. NMR Spectra.
1.5. Electron Spin Resonance Spectra.
1.6. X-Ray Crystallography.
1.7. Molecular Modeling an molecular Mechanics.
2. Intercalating Drugs.
2.1. Acridine Dyes.
2.2. Ethidium Bromide.
2.3. Aclacinomycin.
2.4. Sequence Preference.
2.5. Bis- and Tris- Intercalators.
3. Groove- Binding Drugs.
3.1. Netropsin and Distamycin.
3.2. Derivatives of Netropsin and Distamycin.
3.3. Hoechst 33258, SN6999, and their Derivatives.
3.4. Chromomycin, Mithramycin, and Other GC Binders.
3.5. Groove Binding and Intercalation.
4. Covalent Bonding Drugs.
4.1. (+) CC1065 and Related Drugs.
4.2. Anthramycin and Tomaymycin.
4.3. Ecteinascidins.
4.4. Mitomycins.
4.5. Intercalating Alkylators.
5. Strand-Breaking Drugs.
5.1. Bleomycins.
5.2. Enediyne Antibiotics.
6. Metal-Containing Drugs.
6.1. Cisplatin.
6.2. Cisplatin Derivatives.
6.3. Transplatin and Derivatives.
6.4. Monofunctional Platinum Complexes.
6.5. Polynuclear and High-valent Platinum Complexes.
6.6. Complexes Containing Other Metals.
Appendixes.
Index.
1. DNA Structures and Spectra.
1.1. DNA Structures.
1.2. Electronic Spectra.
1.3. Vibrational Spectra.
1.4. NMR Spectra.
1.5. Electron Spin Resonance Spectra.
1.6. X-Ray Crystallography.
1.7. Molecular Modeling an molecular Mechanics.
2. Intercalating Drugs.
2.1. Acridine Dyes.
2.2. Ethidium Bromide.
2.3. Aclacinomycin.
2.4. Sequence Preference.
2.5. Bis- and Tris- Intercalators.
3. Groove- Binding Drugs.
3.1. Netropsin and Distamycin.
3.2. Derivatives of Netropsin and Distamycin.
3.3. Hoechst 33258, SN6999, and their Derivatives.
3.4. Chromomycin, Mithramycin, and Other GC Binders.
3.5. Groove Binding and Intercalation.
4. Covalent Bonding Drugs.
4.1. (+) CC1065 and Related Drugs.
4.2. Anthramycin and Tomaymycin.
4.3. Ecteinascidins.
4.4. Mitomycins.
4.5. Intercalating Alkylators.
5. Strand-Breaking Drugs.
5.1. Bleomycins.
5.2. Enediyne Antibiotics.
6. Metal-Containing Drugs.
6.1. Cisplatin.
6.2. Cisplatin Derivatives.
6.3. Transplatin and Derivatives.
6.4. Monofunctional Platinum Complexes.
6.5. Polynuclear and High-valent Platinum Complexes.
6.6. Complexes Containing Other Metals.
Appendixes.
Index.
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
