Mouse Models of Human Cancer

Mouse Models of Human Cancer

Holland, Eric C.

John Wiley & Sons Inc

09/2004

488

Dura

Inglês

9780471444602

1358

Descrição não disponível.
Preface.Contributors.PART I: MOUSE HANDLING AND ENGINEERING.1. Approaches to Handling, Breeding, Strain Preservation, Genotyping, and Drug Administration for Mouse Models of Cancer (Dawnalyn Boggess, Kathleen A. Silva, Carlisle P. Landel, Larry Mobraaten, and John P. Sundberg).2. Pathology of Mouse Models of Cancer (Robert D. Cardiff).3. Intercurrent Infections in Genetically Engineered Mice (Stephen W. Barthold).4. Germline Modification Strategies (Silvia Grisendi and Pier Paolo Pandolfi).5. Somatic Cell Gene Transfer (Lene Uhrbom and Eric C. Holland).PART II: ORGAN SITE-SPECIFIC MOUSE MODELS OF HUMAN CANCER.6. Lung Cancer (Jonathan M. Kurie, Parviz Minoo, Stephen S. Hecht, Alexander Nikitin, and Franco J. DeMayo).7. Mammary Gland Cancer (Dalit Barkan, Cristina Montagna, Thomas Ried, and Jeffrey E. Green).8. Prostate Cancer (Katharine Ellwood-Yen and Charles Sawyers).9. Skin Cancer (Marcus Bosenberg).10. Ovarian Cancer (Sandra Orsulic).11. Peripheral Nervous System Tumors (David H. Gutmann, Arie Perry, Reshma Rangwala, and Larry S. Sherman).12. Central Nervous System Tumors (Andrew B. Lassman and Eric C. Holland).13. Myeloid Malignancies (Scott C. Kogan).14. Lymphoid Malignancies (Michael Teitell and Pier Paolo Pandolfi).PART III: GENERAL ISSUES IN CANCER BIOLOGY.15. Genetic Modifiers (David W. Threadgill, Kent W. Hunter, Fei Zou, and Kenneth F. Manly).16. Modeling Blood Vessel Formation in the Mouse (Robert Benezra, Shahin Rafii, and David Lyden).17. Metastasis (Dawn S. Chandler and Guillermina Lozano).18. Immunologic Study of Tumors in Mouse Models (Taha Merghoub and Alan N. Houghton).PART IV: IMAGING TECHNOLOGIES.19. Micro-Computed Tomography of Mouse Cancer Models (Jamey P. Weichert).20 .Magnetic Resonance Imaging in Mouse Cancer Models (Manickam Muruganandham and Jason A. Koutcher).21. Bioluminescent Imaging of Mouse Cancer Models (Christopher H. Contag).PART V: PRECLINICAL TRIALS.22 .Use of Magnetic Resonance Imaging for Evaluation of Treatment Response (Brian D. Ross, Thomas L. Chenevert, Bradford A. Moffat, Alnawaz Rehemtulla, Daniel E. Hall, Patrick McConville, and Jonathan Moody).23. Physiologically Based Pharmacokinetic and Pharmacodynamic Modeling (Raymond S. H. Yang, James E. Dennison, Melvin E. Andersen, Ying C. Ou, Kai H. Liao, and Brad Reisfeld).24. Trial Design and Biostatistics (Michael F. W. Festing).25. Cancer Drug Development in the Modern Era (William R. Sellers and Alex Matter).26. Preclinical Trials in Mouse Cancer Models (Brian Weiss and Kevin Shannon).Index.
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mice; host environment; complex; tumor; choice; between; species; interactions; mouse genetics; technology; growing array; purpose; causal; models; mouse; alterations; genetic; investigators; allow; specific; new; development; lines